On the inference of spatial structure from population genetics data using the Tess program
نویسندگان
چکیده
Motivation: In a series of recent papers, Tess, a computer program based on the concept of hidden Markov random field, has been proposed to infer the number and locations of panmictic population units from the genotypes and spatial locations of these individuals. The method seems to be of broad appeal as it is conceptually much simpler than other competing methods and it has been reported by its authors to be fast and accurate. However, this methodology is not grounded in a formal statistical inference method and seems to rely to a large extent on arbitrary choices regarding the parameters used. The present article is an investigation of the accuracy of this method and an attempt to assess whether recent results reported on the basis of this method are genuine features of the genetic process or artefacts
منابع مشابه
TESS3: fast inference of spatial population structure and genome scans for selection.
Geography and landscape are important determinants of genetic variation in natural populations, and several ancestry estimation methods have been proposed to investigate population structure using genetic and geographic data simultaneously. Those approaches are often based on computer-intensive stochastic simulations and do not scale with the dimensions of the data sets generated by high-throug...
متن کاملComment on 'On the inference of spatial structure from population genetics data'
TESS is a Bayesian clustering program for population genetic analyses which assumes Kmax clusters and computes posterior estimates for membership coefficients or admixture proportions by updating spatially explicit prior distributions (Chen et al., 2007; François et al., 2006). Version 2.1 of the program was released in January 2009 (Durand et al., 2009a, b). The program applies principles of B...
متن کاملOn the inference of spatial structure from population genetics data
MOTIVATION In a series of recent papers, Tess, a computer program based on the concept of hidden Markov random field, has been proposed to infer the number and locations of panmictic population units from the genotypes and spatial locations of these individuals. The method seems to be of broad appeal as it is conceptually much simpler than other competing methods and it has been reported by its...
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